nicotinic acid
Classification:
Product Description
Specification parameters

essential information
Niacin belongs to the vitamin B family, also known as niacin, vitamin B3, and anti leprosy factor. Its molecular formula is C6H5NO2 and its chemical name is pyridine-3-carboxylic acid. It has good thermal stability and can sublime. In industry, the sublimation method is commonly used to purify niacin. Niacin appears as white crystals or white crystalline powder, soluble in water, mainly present in animal organs, muscle tissues, fruits, and egg yolks in trace amounts. It is one of the 13 essential vitamins for the human body.
At present, niacin is mainly used as a feed additive to improve the utilization rate of feed protein, increase milk production in dairy cows, and improve the yield and quality of meat in poultry and livestock such as fish, chicken, duck, cattle, and sheep. Niacin is also a widely used pharmaceutical intermediate, which can be used as a raw material to synthesize various medicines, such as nicotinamide and nicotinamide inositol ester. In addition, niacin plays an irreplaceable role in the fields of luminescent materials, dyes, and electroplating industries.
application area
Niacin has three product specifications, namely food grade, feed grade, and pharmaceutical grade. Niacin is mainly used as a nutritional additive (water-soluble vitamin) in feed, as well as an intermediate in food, medicine, and dyes. It is also used as an additive in electroplating solutions and biochemical reagents.
Application of Niacin in Pharmaceutical Synthesis
Niacin, as a medication, can prevent and treat skin diseases and similar vitamin deficiencies. It has the effect of dilating blood vessels and is used to treat conditions such as peripheral nerve spasms and arteriosclerosis. Niacin can also be used as a pharmaceutical intermediate for the synthesis of various amide and ester drugs with important pharmaceutical applications. Niacin amide can be used to treat gastrointestinal diseases, nicotinic acid hydroxymethylamine is a good medicine for liver protection, bile retention, and antibacterial effects, and nicotinic acid phenylmethylamine is an efficient snail killing drug that can be used to prevent and treat schistosomiasis; Niacin and tromethamine can be synthesized into drugs for the treatment of circulatory system disorders, vitamin B deficiency, glossitis, hypertension, and other diseases; Nicotinic acid and diethylamine synthesized nicotinamide are central nervous system stimulants used to treat central nervous system respiratory and circulatory system failure; Nicotinic acid reacts with alcohol to produce nicotinate inositol ester and metronidazole, which are drugs used to treat hyperlipidemia, coronary heart disease, migraine, peripheral vascular disorders, and other conditions.
Application of Niacin as an Adjuvant
Niacin is an essential food and feed additive for human and animal growth and development. Therefore, niacin is widely used as an additive in cakes, dairy products, corn flour, etc; Niacin can also be used in combination with vitamins to replace some nitrites as a deodorizer or preservative for meat products. In addition, niacin can also be used as a preservative for vegetables. Due to the fact that a large portion of niacin in cereal feed exists in complex form, it cannot be directly absorbed by animals. Therefore, the commonly used method in the world is to add synthetic niacin to feed. Through feed feeding experiments, it has been proven that artificially synthesized niacin can be absorbed and utilized 100% by animals, and can achieve significant weight gain effects in a short period of time. According to the situation of China's animal husbandry industry, the standard for adding niacin is 9-24mg per kg of pig feed (dry basis) and 10-27mg per kg of chicken feed (dry basis).
food additives
Niacin belongs to the vitamin B family and is involved in the body's lipid metabolism, oxidation processes, and anaerobic decomposition processes. Niacin can be converted from tryptophan in the body, and the human body is generally not prone to niacin deficiency. However, when the staple food does not contain niacin or contains substances that decompose niacin, it can easily lead to rough skin diseases caused by niacin deficiency. Therefore, nicotinic acid is widely used in flour processing, dairy products and corn meal production. Adding a certain amount of niacin to food can effectively prevent the occurrence of such diseases.
feed additive
Niacin is an essential substance for animal growth and development. Niacin in cereal feed mainly exists in bound form, which is difficult for animals to absorb. Therefore, synthetic niacin needs to be artificially added to feed. Adding an appropriate amount of niacin to feed can rapidly increase the weight of piglets (chickens). Feeding laying hens with niacin feed can increase their egg production rate and also increase the nutritional value of eggs containing a certain amount of niacin.
reactive dye
Because niacin can make fiber dyeing durable, widely applicable, and uniform, it has outstanding performance in the dye industry and has become an intermediate for various reactive dyes. In 1984, a Japanese pharmaceutical company launched a weakly alkaline nicotinic acid triazine reactive dye.
Daily chemical industrial products
In the daily chemical industry, niacin can be formulated with other daily chemical raw materials to produce high-performance products, such as hair dye additives, detergents, etc.
Other applications
Niacin is an important chemical additive and corrosion inhibitor, which can be used as an antioxidant and anti fog agent in photosensitive materials. Niacin is also an excellent brightening additive during electroplating, and adding 1-10g of niacin per liter of electroplating solution has a significant effect. Niacin is used as an antioxidant and anti fog agent in photosensitive materials. Adding 0.1% aqueous nicotinic acid solution to the photosensitive lotion can increase the stability of the photosensitive material to light; Adding 5-20mL 0.1% nicotinic acid aqueous solution to each milliliter of photosensitive lotion can reduce the fog of photosensitive materials.
Packaging, Storage, Transportation, and Safety
Sealed storage.